Nrf2 Detox 60 Capsules
Nrf2 Detox 60 Capsules
Cruciferous vegetables of the brassica family have long been recognized for their ability to support detoxification thereby maintaining healthy cells and tissues. Cruciferous vegetables, like broccoli, cauliflower, Brussels sprouts and kale, are the richest sources of glucosinolates, which are considered to be the most bioactive constituents. Glucosinolates are converted in the body to isothiocyanates after they are ingested and hydrolyzed. The isothiocyanate sulforaphane is one of the most powerful activators of phase II enzyme function in the liver, supporting toxin elimination. Sulforaphane and resveratrol promote the activity of nuclear factor erythroid 2-related factor 2 (Nrf2), a transcription factor that supports robust, long-lasting expression of numerous genes responsible for detoxification and protection against oxidative stress. Among these genes are glutathione peroxidase, superoxide dismutase and various phase II enzymes, such as glutathione sulfotransferases. Nrf2 also supports expression of glutathione glutamylcysteinyl ligase, which is responsible for a critical step in the biosynthesis of glutathione, a vital component of cellular antioxidant and detoxification systems. Found in virtually every cell of the body, glutathione plays essential roles in protein synthesis, synthesis and repair of DNA, enzyme function, transport, and cell maturation. Optimal levels of glutathione have been associated with physical and mental health. The highest concentration of glutathione is found in the liver, where it offers antioxidant support, protects tissue and maintains detoxification. In a randomized clinical trial, supplementation with 250 and 1, 000 mg of Setria® glutathione per day increased glutathione levels in the blood after one, three and six months. At six months, mean glutathione levels in the high-dose group increased 30-35% in erythrocytes, plasma and lymphocytes, and 260% in buccal cells (P<0.05). In the low-dose group, mean glutathione levels increased 17% and 29% in blood and erythrocytes, respectively (P<0.05). Both glutathione dose groups showed support for antioxidant defenses, indicated by decreases in the oxidized-to-reduced-glutathione ratio in whole blood after six months.*
Take 1 capsule, 1-3 times daily, with meals.
Serving Size: One Capsule
Amount Per Serving
Broccoli sprout concentrate ... 250mg
(Brassica oleracea italica)(whole plant)
(standardized to contain 1, 000mcg sulforaphane)
Setria® glutathione ... 250mg
ResVida® resveratrol ... 15mg
Other Ingredients: vegetarian capsule (cellulose, water)
This product does not contain
- artificial additives
- environmental contaminants
- added excipients
Use only if safety seal is intact.
If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.
KEEP OUT OF REACH OF CHILDREN
Store sealed in a cool dry area
Setria® is a registered trademark of KYOWA HAKKO BIO Co., Ltd.
resVida® This product contains resVida®. resVida® is a registered trademark of DSM Nutritional Products, Inc.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.